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Diagnostic Accuracy of Ten Second-Generation (Human) Tissue Transglutaminase Antibody Assays in Celiac Disease
Author(s) -
Britta Van Meensel,
Martin Hiele,
Ilse Hoffman,
Séverine Vermeire,
Paul Rutgeerts,
Karel Geboes,
Xavier Bossuyt
Publication year - 2004
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.035832
Subject(s) - tissue transglutaminase , endomysium , gliadin , medicine , antibody , antigen , immunopathology , immunology , biopsy , immunoglobulin a , gluten , coeliac disease , gastroenterology , immunoglobulin g , disease , pathology , biology , biochemistry , enzyme
Anti-tissue transglutaminase (tTG) assays that use human tTG as antigen have recently become available. We evaluated commercially available assays with human tTG antigen to estimate their diagnostic accuracies and to determine whether they agree sufficiently to be used interchangeably.

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