Gene Expression Analysis in Platelets from a Single Donor: Evaluation of a PCR-Based Amplification Technique | Zendy

Jutta M. Rox | Zendy; Peter Bugert | Zendy; Jens Müller | Zendy; Alexander Schorr | Zendy; Peter Hanfland | Zendy; Katharina Madlener | Zendy; Harald Klüter | Zendy; Bernd Pötzsch | Zendy

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Gene Expression Analysis in Platelets from a Single Donor: Evaluation of a PCR-Based Amplification Technique

Author(s) -

Jutta M. Rox,

Peter Bugert,

Jens Müller,

Alexander Schorr,

Peter Hanfland,

Katharina Madlener,

Harald Klüter,

Bernd Pötzsch

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.035386

Subject(s) - microbiology and biotechnology , platelet , rna , glyceraldehyde 3 phosphate dehydrogenase , gene expression , biology , gene , gene expression profiling , rna extraction , messenger rna , chemistry , biochemistry , immunology

Genetic analysis of platelet mRNA may facilitate the diagnosis of disorders affecting the megakaryocytic-platelet lineage. Its use, however, is limited by the exceptionally small yield of platelet mRNA and the risk of leukocyte contamination during platelet preparation.

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