Development of Sensitive Immunoassays for Free and Total Human Glandular Kallikrein 2 | Zendy

Ville Väisänen | Zendy; Susann Eriksson | Zendy; Kaisa K. Ivaska | Zendy; Hans Lilja | Zendy; Martti Nurmi | Zendy; Kim Pettersson | Zendy

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Development of Sensitive Immunoassays for Free and Total Human Glandular Kallikrein 2

Author(s) -

Ville Väisänen,

Susann Eriksson,

Kaisa K. Ivaska,

Hans Lilja,

Martti Nurmi,

Kim Pettersson

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.035253

Subject(s) - prostate cancer , prostate specific antigen , antibody , prostate , monoclonal antibody , antigen , detection limit , medicine , andrology , cancer , chemistry , urology , immunology , chromatography

Free and total human kallikrein 2 (hK2) might improve the discrimination between prostate cancer and benign prostatic hyperplasia. Concentrations of hK2 are 100-fold lower than concentrations of prostate-specific antigen (PSA); therefore, an hK2 assay must have a low detection limit and good specificity.

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