Open AccessDistribution Spectrum of Paraoxonase Activity in HDL Fractions
Author(s) -
Christoph Bergmeier,
R. Siekmeier,
Werner Groß
Publication year - 2004
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.034439
Subject(s) - pon1 , paraoxonase , chemistry , cholesterol , aryldialkylphosphatase , fractionation , high density lipoprotein , fraction (chemistry) , chromatography , enzyme , biochemistry , genotype , gene
Paraoxonase (PON1) associated with HDL can be regarded as a cardio- and vasoprotective enzyme. However, because HDL is not a homogeneous fraction, it is important to investigate in which subgroups of HDL active PON1 is located. It would also be useful to determine density profiles of the HDL apolipoproteins (Apo) E and J.
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