Rapid Screening Test for Primary Hyperaldosteronism: Ratio of Plasma Aldosterone to Renin Concentration Determined by Fully Automated Chemiluminescence Immunoassays | Zendy

F. H. Perschel | Zendy; Rudolf Schemer | Zendy; L Seiler | Zendy; Martín Reincke | Zendy; Jaap Deinum | Zendy; Christiane MaserGluth | Zendy; David Mechelhoff | Zendy; R Tauber | Zendy; Sven Diederich | Zendy

Open Access

Rapid Screening Test for Primary Hyperaldosteronism: Ratio of Plasma Aldosterone to Renin Concentration Determined by Fully Automated Chemiluminescence Immunoassays

Author(s) -

F. H. Perschel,

Rudolf Schemer,

L Seiler,

Martín Reincke,

Jaap Deinum,

Christiane MaserGluth,

David Mechelhoff,

R Tauber,

Sven Diederich

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.033159

Subject(s) - hyperaldosteronism , chemiluminescence , aldosterone , endocrinology , primary aldosteronism , medicine , plasma renin activity , renin–angiotensin system , screening test , chemistry , chromatography , pediatrics , blood pressure

The ratio of plasma aldosterone concentration to plasma renin activity (PAC/PRA) is the most common screening test for primary hyperaldosteronism (PHA), but it is not standardized among laboratories. We evaluated new automated assays for the simultaneous measurement of PAC and plasma renin concentration (PRC).

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