Homocysteine Is Lower in the Third Trimester of Pregnancy in Women with Enhanced Folate Status from Continued Folic Acid Supplementation | Zendy

Valerie Holmes | Zendy; Julie Wallace | Zendy; H. Denis Alexander | Zendy; William S. Gilmore | Zendy; Ian Bradbury | Zendy; Mary Ward | Zendy; John M. Scott | Zendy; P. McFaul | Zendy; Helene McNulty | Zendy

Open Access

Homocysteine Is Lower in the Third Trimester of Pregnancy in Women with Enhanced Folate Status from Continued Folic Acid Supplementation

Author(s) -

Valerie Holmes,

Julie Wallace,

H. Denis Alexander,

William S. Gilmore,

Ian Bradbury,

Mary Ward,

John M. Scott,

P. McFaul,

Helene McNulty

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.032698

Subject(s) - pregnancy , medicine , homocysteine , gestation , hyperhomocysteinemia , neural tube defect , obstetrics , preeclampsia , miscarriage , endocrinology , physiology , fetus , biology , genetics

In many countries, current recommendations are that women take a daily 400-mug folic acid supplement from before conception until the end of the 12th week of gestation for the prevention of neural tube defects. Low folate status is associated with an increased concentration of plasma total homocysteine (tHcy), a risk factor associated with pregnancy complications such as preeclampsia.

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