Evaluation of Two Nonisotopic Immunoassays for Determination of Glutamic Acid Decarboxylase and Tyrosine Phosphatase Autoantibodies in Serum | Zendy

Xavier Palomer | Zendy; Dı́dac Mauricio | Zendy; José Rodrı́guez-Espinosa | Zendy; Edgar Zapico | Zendy; Carme Mayoral | Zendy; Francesc GonzálezSastre | Zendy; Alberto de Leiva | Zendy; Francisco BlancoVaca | Zendy

Open Access

Evaluation of Two Nonisotopic Immunoassays for Determination of Glutamic Acid Decarboxylase and Tyrosine Phosphatase Autoantibodies in Serum

Author(s) -

Xavier Palomer,

Dı́dac Mauricio,

José Rodrı́guez-Espinosa,

Edgar Zapico,

Carme Mayoral,

Francesc GonzálezSastre,

Alberto de Leiva,

Francisco BlancoVaca

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.031799

Subject(s) - autoantibody , medicine , type 1 diabetes , diabetes mellitus , glutamate decarboxylase , antibody , endocrinology , confidence interval , immunology , biology , biochemistry , enzyme

Autoantibodies for the 65-kDa form of glutamic acid decarboxylase (GAD65) and protein tyrosine phosphatase-like protein (IA-2) are measured for risk prediction and diagnosis of autoimmune diabetes mellitus. There is a lack of adequate nonisotopic alternatives to the most widely used method for both autoantibodies, which is a radiobinding assay (RBA).

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