Brain- and Heart-Type Fatty Acid-Binding Proteins in the Brain: Tissue Distribution and Clinical Utility | Zendy

Maurice M. A. L. Pelsers | Zendy; Thorsten Hanhoff | Zendy; D. van der Voort | Zendy; Baer Arts | Zendy; Maarten Peters | Zendy; Rudolf Ponds | Zendy; Adriaan Honig | Zendy; Wojtek Rudzinski | Zendy; Friedrich Spener | Zendy; Jelle R. de Kruijk | Zendy; A. Twijnstra | Zendy; Wim Th. Hermens | Zendy; Paul P.C.A. Menheere | Zendy; Jan F. C. Glatz | Zendy

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Brain- and Heart-Type Fatty Acid-Binding Proteins in the Brain: Tissue Distribution and Clinical Utility

Author(s) -

Maurice M. A. L. Pelsers,

Thorsten Hanhoff,

D. van der Voort,

Baer Arts,

Maarten Peters,

Rudolf Ponds,

Adriaan Honig,

Wojtek Rudzinski,

Friedrich Spener,

Jelle R. de Kruijk,

A. Twijnstra,

Wim Th. Hermens,

Paul P.C.A. Menheere,

Jan F. C. Glatz

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2003.030361

Subject(s) - enolase , heart type fatty acid binding protein , glial fibrillary acidic protein , pons , fatty acid binding protein , pathology , cerebellum , medicine , striatum , chemistry , endocrinology , biochemistry , immunohistochemistry , gene , dopamine

Detection of brain injury by serum markers is not a standard procedure in clinical practice, although several proteins, such as S100B, neuron-specific enolase (NSE), myelin basic protein, and glial fibrillary acidic protein, show promising results. We investigated the tissue distribution of brain- and heart-type fatty acid-binding proteins (B-FABP and H-FABP) in segments of the human brain and the potential of either protein to serve as plasma marker for diagnosis of brain injury.

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