Open AccessBetween-Method Variation in Human Chorionic Gonadotropin Test Results
Author(s) -
Laurence A. Cole,
Jaime M. Sutton,
Trefor Higgins,
George S. Cembrowski
Publication year - 2004
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2003.026989
Subject(s) - human chorionic gonadotropin , gene isoform , gonadotropin , isoelectric focusing , chemistry , endocrinology , immunoassay , andrology , medicine , biology , hormone , biochemistry , enzyme , immunology , antibody , gene
Results on sera and calibrators vary 1.4- to 2.3-fold among commercial human chorionic gonadotropin (hCG) assays. The relative contributions of calibrators, standards, hCG charge isoforms, and major structural variants to this variation have not been quantified.
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