Proenzyme Forms of Prostate-Specific Antigen in Serum Improve the Detection of Prostate Cancer | Zendy

Stephen D. Mikolajczyk | Zendy; William J. Catàlona | Zendy; Cindy L. Evans | Zendy; Harry J. Linton | Zendy; Lisa S. Millar | Zendy; Kathy M. Marker | Zendy; Diksha Katir | Zendy; Anna Amirkhan | Zendy; Harry G. Rittenhouse | Zendy

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Proenzyme Forms of Prostate-Specific Antigen in Serum Improve the Detection of Prostate Cancer

Author(s) -

Stephen D. Mikolajczyk,

William J. Catàlona,

Cindy L. Evans,

Harry J. Linton,

Lisa S. Millar,

Kathy M. Marker,

Diksha Katir,

Anna Amirkhan,

Harry G. Rittenhouse

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2003.026823

Subject(s) - prostate cancer , medicine , prostate specific antigen , cancer , prostate , confidence interval , antigen , monoclonal antibody , antibody , area under the curve , urology , gastroenterology , immunology

Pro or precursor forms of prostate-specific antigen (PSA) have emerged as potentially important diagnostic serum markers for prostate cancer detection. Immunoassays were developed to measure specific proPSA forms containing propeptides of 2, 4, and 7 amino acids [(-2)proPSA, (-4)proPSA, and (-7)proPSA, respectively].

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