Real-Time Quantitative Reverse Transcription-PCR for Cyclin D1 mRNA in Blood, Marrow, and Tissue Specimens for Diagnosis of Mantle Cell Lymphoma
Author(s) -
John Greg Howe,
Jill Crouch,
Dennis Cooper,
Brian R. Smith
Publication year - 2004
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2003.024695
Subject(s) - cyclin d1 , mantle cell lymphoma , bone marrow , biology , messenger rna , real time polymerase chain reaction , lymph node , microbiology and biotechnology , cyclin , cancer research , lymphoma , pathology , medicine , immunology , cell cycle , cell , gene , genetics
Overexpression of cyclin D1 mRNA, found in mantle cell lymphoma (MCL), is a critical diagnostic marker. We investigated the use of real-time reverse transcription-PCR (RT-PCR) for cyclin D1.
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