Pharmacodynamic Approach to Immunosuppressive Therapies Using Calcineurin Inhibitors and Mycophenolate Mofetil | Zendy

Olga Millán | Zendy; Merçè Brunet | Zendy; Josep M. Campistol | Zendy; Ana Faura | Zendy; Isabel Rojo | Zendy; Elena Vidal | Zendy; Olga Jiménez | Zendy; Jordi Vives | Zendy; F Oppenheimer | Zendy; Jaume Martorell | Zendy

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Pharmacodynamic Approach to Immunosuppressive Therapies Using Calcineurin Inhibitors and Mycophenolate Mofetil

Author(s) -

Olga Millán,

Merçè Brunet,

Josep M. Campistol,

Ana Faura,

Isabel Rojo,

Elena Vidal,

Olga Jiménez,

Jordi Vives,

F Oppenheimer,

Jaume Martorell

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2003.021725

Subject(s) - calcineurin , mycophenolate , mycophenolic acid , pharmacology , tacrolimus , medicine , pharmacodynamics , immunosuppression , cmax , peripheral blood mononuclear cell , whole blood , cmin , pharmacokinetics , transplantation , chemistry , in vitro , biochemistry

Graft survival depends on adequate immunosuppression. To evaluate the effect on the immune system of immunosuppressive therapies using calcineurin inhibitors (CNIs), several pharmacodynamic indices have been proposed to complement pharmacokinetic data. In this preliminary study we compared some of these parameters during combined immunosuppressant therapies.

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