Regulation of Serum Paraoxonase Activity by Genetic, Nutritional, and Lifestyle Factors in the General Population
Author(s) -
Natàlia Ferré,
Jordi Camps,
Joan FernándezBallart,
Victoria Arija,
Michelle M. Murphy,
Santiago Ceruelo,
Elisabet Biarnés,
Elisabet Vilella,
Mònica Tous,
Jorge Joven
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.9.1491
Subject(s) - paraoxonase , body mass index , medicine , endocrinology , cholesterol , population , aryldialkylphosphatase , pon1 , biology , oxidative stress , biochemistry , genotype , environmental health , gene
Paraoxonase may protect lipoproteins and cell membranes from peroxidation, and alterations in the activity of this enzyme have been associated with some chronic diseases. Serum paraoxonase appears to be mainly under genetic control, but some studies suggest that environmental factors may also modulate its activity. The aim of the present study was to investigate whether diet and lifestyle affect serum paraoxonase activity.
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