Time Course of Early and Late Changes in Plasma DNA in Trauma Patients
Author(s) -
Nicole Y.L. Lam,
Timothy H. Rainer,
Lisa Chan,
Gavin M. Joynt,
Y. M. Dennis Lo
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.8.1286
Subject(s) - multiple organ dysfunction syndrome , medicine , intensive care unit , organ dysfunction , injury severity score , gastroenterology , poison control , injury prevention , emergency medicine , sepsis
Cell-free DNA concentrations increase in the circulation of patients after trauma and may have prognostic potential, but little is know concerning the temporal changes or clearance of the DNA or its relationships with posttraumatic complications. We investigated temporal changes in plasma DNA concentrations in patients after trauma with use of real-time quantitative PCR.
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