Practical Considerations for the Measurement of Free Light Chains in Serum
Author(s) -
Jillian R. Tate,
Devinder Gill,
Ralph Cobcroft,
Peter E. Hickman
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.8.1252
Subject(s) - immunoglobulin light chain , monoclonal gammopathy of undetermined significance , multiple myeloma , monoclonal , immunoassay , medicine , plasmacytoma , monoclonal antibody , transplantation , coefficient of variation , immunology , oncology , antibody , chemistry , chromatography
A new immunoassay for free light chain measurements has been reported to be useful for the diagnosis and monitoring of monoclonal light chain diseases and nonsecretory myeloma. We describe experience with and some potential pitfalls of the assay.
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