Optimal Sampling Strategies to Assess Inulin Clearance in Children by the Inulin Single-Injection Method | Zendy

L. K. van Rossum | Zendy; Ron A. A. Mathôt | Zendy; Karlien Cransberg | Zendy; Arnold G. Vulto | Zendy

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Optimal Sampling Strategies to Assess Inulin Clearance in Children by the Inulin Single-Injection Method

Author(s) -

L. K. van Rossum,

Ron A. A. Mathôt,

Karlien Cransberg,

Arnold G. Vulto

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.7.1170

Subject(s) - inulin , sampling (signal processing) , chromatography , chemistry , food science , computer science , filter (signal processing) , computer vision

Glomerular filtration rate in patients can be determined by estimating the plasma clearance of inulin with the single-injection method. In this method, a single bolus injection of inulin is administered and several blood samples are collected. For practical and convenient application of this method in children, it is important that a minimal number of samples are drawn. The aim of this study was to develop and validate sampling strategies with fewer samples for reliable prediction of inulin clearance in pediatric patients by the inulin single-bolus-injection method.

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