Negative Interference in Cardiac Troponin I Immunoassays from a Frequently Occurring Serum and Plasma Component | Zendy

Susann Eriksson | Zendy; Miia Junikka | Zendy; Päivi Laitinen | Zendy; Kirsi MajamaaVoltti | Zendy; Henrik Alfthan | Zendy; Kim Pettersson | Zendy

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Negative Interference in Cardiac Troponin I Immunoassays from a Frequently Occurring Serum and Plasma Component

Author(s) -

Susann Eriksson,

Miia Junikka,

Päivi Laitinen,

Kirsi MajamaaVoltti,

Henrik Alfthan,

Kim Pettersson

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.7.1095

Subject(s) - troponin i , epitope , antibody , troponin , immunoassay , acute coronary syndrome , medicine , myocardial infarction , microbiology and biotechnology , chemistry , immunology , biology

Cardiac troponin I (cTnI) is a sensitive marker of cardiac injury, but cTnI assays, like other immunoassays, are susceptible to interferences. We evaluated the presence of interfering substances by measuring the recovery of cTnI added to samples from volunteers and from patients with acute coronary syndromes (ACS).

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