Time-resolved Fluorometric Assay for Detection of Autoantibodies to Glutamic Acid Decarboxylase (GAD65)
Author(s) -
Matti Ankelo,
Annette WesterlundKarlsson,
Jorma Ilonen,
Mikael Knip,
K. Savola,
Pasi Kankaanpää,
Liisa Meriö,
Harri Siitari,
Ari Hinkkanen
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.6.908
Subject(s) - glutamate decarboxylase , autoantibody , chemistry , biochemistry , carboxy lyases , enzyme , chromatography , microbiology and biotechnology , biology , antibody , immunology
Type 1 diabetes mellitus results from destruction of the pancreatic insulin-producing beta cells by a chronic autoimmune process. Methods are needed for the detection of circulating autoantibodies to glutamic acid decarboxylase (GAD65), a major marker of this process.
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