Genotype-specific Influence on Nitric Oxide Synthase Gene Expression, Protein Concentrations, and Enzyme Activity in Cultured Human Endothelial Cells | Zendy

Junghan Song | Zendy; Yeomin Yoon | Zendy; Kyoung Un Park | Zendy; Junwan Park | Zendy; Young Joon Hong | Zendy; Seung Ho Hong | Zendy; Jin Q Kim | Zendy

Open Access

Genotype-specific Influence on Nitric Oxide Synthase Gene Expression, Protein Concentrations, and Enzyme Activity in Cultured Human Endothelial Cells

Author(s) -

Junghan Song,

Yeomin Yoon,

Kyoung Un Park,

Junwan Park,

Young Joon Hong,

Seung Ho Hong,

Jin Q Kim

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.6.847

Subject(s) - microbiology and biotechnology , genotype , umbilical vein , biology , exon , intron , gene expression , gene , biochemistry , in vitro

The results of studies on the association of ecNOS polymorphisms and vascular diseases are inconsistent. To explore the nature of this interaction in the absence of confounding factors, such as smoking, we measured ecNOS mRNA, protein, and enzyme activity in cultured human umbilical vein endothelial cells (HUVECs) with and without ecNOS polymorphisms.

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