Open AccessRapid Detection of β-Globin Gene Mutations and Polymorphisms by Temporal Temperature Gradient Gel Electrophoresis
Author(s) -
Shaji R Velayudhan,
Eunice Sindhuvi Edison,
Poonkuzhali Balasubramanian,
Alok Srivastava,
Mammen Chandy
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.5.777
Subject(s) - genetics , mutation , beta thalassemia , biology , gene , thalassemia , allele , microbiology and biotechnology , gene mutation
Inherited hemoglobin disorders represent the most common Mendelian disease worldwide. Prevention programs based on molecular diagnosis of heterozygous carriers and/or patients require the use of reliable mutation scanning methods in at-risk populations.
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