Evaluation of Electronic Microarrays for Genotyping Factor V, Factor II, and MTHFR | Zendy

Maria Erali | Zendy; Ben Schmidt | Zendy; Elaine Lyon | Zendy; Carl T. Wittwer | Zendy

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Evaluation of Electronic Microarrays for Genotyping Factor V, Factor II, and MTHFR

Author(s) -

Maria Erali,

Ben Schmidt,

Elaine Lyon,

Carl T. Wittwer

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.5.732

Subject(s) - methylenetetrahydrofolate reductase , genotype , genotyping , biology , factor v , microbiology and biotechnology , genetics , factor v leiden , dna microarray , mutation , gene , medicine , venous thrombosis , gene expression , thrombosis

Genetic risk factors associated with venous thrombosis include mutations in the factor V (Leiden), factor II (prothrombin), and methylenetetrahydrofolate reductase (MTHFR) genes. We evaluated a method using electronically addressable microarrays for the detection of mutations in these genes that have been associated with vascular disease.

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