Standardization of Immunoassays for Measurement of High-Sensitivity C-reactive Protein. Phase I: Evaluation of Secondary Reference Materials | Zendy

Mary M. Kimberly | Zendy; Hubert W. Vesper | Zendy; Samuel P. Caudill | Zendy; Gerald R. Cooper | Zendy; Nader Rifai | Zendy; Francesco Dati | Zendy; Gary L. Myers | Zendy

Open Access

Standardization of Immunoassays for Measurement of High-Sensitivity C-reactive Protein. Phase I: Evaluation of Secondary Reference Materials

Author(s) -

Mary M. Kimberly,

Hubert W. Vesper,

Samuel P. Caudill,

Gerald R. Cooper,

Nader Rifai,

Francesco Dati,

Gary L. Myers

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.4.611

Subject(s) - c reactive protein , certified reference materials , medicine , standardization , immunoassay , population , acute phase protein , chromatography , inflammation , detection limit , immunology , chemistry , computer science , antibody , environmental health , operating system

Inflammation contributes to the development and progression of atherosclerosis, and C-reactive protein (CRP) can be used as a marker to assess risk for cardiovascular diseases. As variability among existing high-sensitivity CRP (hsCRP) assays can lead to misclassification of patients and hamper implementation of population-based medical decision points, standardization of hsCRP assays is needed.

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