Standardization of Two Immunoassays for Human Glandular Kallikrein 2 | Zendy

Alexander Haese | Zendy; Ville Väisänen | Zendy; Judith A. Finlay | Zendy; Kim Pettersson | Zendy; Harry G. Rittenhouse | Zendy; Alan W. Partin | Zendy; Debra J. Bruzek | Zendy; Lori J. Sokoll | Zendy; Hans Lilja | Zendy; Daniel W. Chan | Zendy

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Standardization of Two Immunoassays for Human Glandular Kallikrein 2

Author(s) -

Alexander Haese,

Ville Väisänen,

Judith A. Finlay,

Kim Pettersson,

Harry G. Rittenhouse,

Alan W. Partin,

Debra J. Bruzek,

Lori J. Sokoll,

Hans Lilja,

Daniel W. Chan

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.4.601

Subject(s) - confidence interval , serial dilution , chromatography , microbiology and biotechnology , biology , chemistry , medicine , pathology , alternative medicine

Measurement of human kallikrein 2 (hK2) has improved early detection and staging of prostate cancer. However, reported concentrations of hK2 among currently used assays have not been standardized in any way. We compared two hK2 assays and five different recombinant hK2 variants (rhK2) and suggest a common calibrator as an important step and putative reference substance in hK2 assay standardization.

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