Low-Positive Anti-Hepatitis C Virus Enzyme Immunoassay Results: An Important Predictor of Low Likelihood of Hepatitis C Infection | Zendy

D. Robert Dufour | Zendy; Mageli Talastas | Zendy; Maria D A Fernandez | Zendy; Barbara J. Harris | Zendy; Doris B. Strader | Zendy; Leonard B. Seeff | Zendy

Open Access

Low-Positive Anti-Hepatitis C Virus Enzyme Immunoassay Results: An Important Predictor of Low Likelihood of Hepatitis C Infection

Author(s) -

D. Robert Dufour,

Mageli Talastas,

Maria D A Fernandez,

Barbara J. Harris,

Doris B. Strader,

Leonard B. Seeff

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.3.479

Subject(s) - hepatitis c virus , medicine , hepatitis c , immunoassay , antibody , gastroenterology , flaviviridae , titer , hepacivirus , virology , immunology , virus

Tests for hepatitis C antibodies (anti-HCV enzyme immunoassays) are usually described as positive or negative. Several studies, mainly in blood donors, have found that specimens with low signal/cutoff (S/C) ratios are commonly negative when tested with a recombinant immunoblot assay (RIBA) or for HCV RNA.

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