Endothelial Nitric Oxide Synthase Gene Polymorphisms and Risk of Coronary Artery Disease
Author(s) -
Maria Giovanna Colombo,
Umberto Paradossi,
Maria Grazia Andreassi,
Nicoletta Botto,
Samantha Manfredi,
Serena Masetti,
Andrea Biagini,
Aldo Clerico
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.3.389
Subject(s) - enos , odds ratio , allele , coronary artery disease , genotype , linkage disequilibrium , medicine , gastroenterology , biology , haplotype , allele frequency , endocrinology , genetics , nitric oxide synthase , nitric oxide , gene
Endothelial nitric oxide synthase (eNOS) could be a candidate gene for coronary artery disease (CAD). This study investigated the relationship of the eNOS Glu(298)-->Asp and T(786)-->C polymorphisms with the presence and severity of CAD in the Italian population.
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