Detecting Subsecond Dopamine Release with Fast-Scan Cyclic Voltammetry in Vivo | Zendy

Donita L. Robinson | Zendy; B. Jill Venton | Zendy; Michael L. Heien | Zendy; R. Mark Wightman | Zendy

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Detecting Subsecond Dopamine Release with Fast-Scan Cyclic Voltammetry in Vivo

Author(s) -

Donita L. Robinson,

B. Jill Venton,

Michael L. Heien,

R. Mark Wightman

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.10.1763

Subject(s) - dopamine , cyclic voltammetry , in vivo , voltammetry , chemistry , neuroscience , biophysics , electrode , biology , electrochemistry , microbiology and biotechnology

Dopamine is a potent neuromodulator in the brain, influencing a variety of motivated behaviors and involved in several neurologic diseases. Measurements of extracellular dopamine in the brains of experimental animals have traditionally focused on a tonic timescale (minutes to hours). However, dopamine concentrations are now known to fluctuate on a phasic timescale (subseconds to seconds).

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