Homogeneous Real-Time Detection of Single-Nucleotide Polymorphisms by Strand Displacement Amplification on the BD ProbeTec ET System | Zendy

Shasha Wang | Zendy; Keith Thornton | Zendy; Andrew M. Kuhn | Zendy; James G. Nadeau | Zendy; T. J. Hellyer | Zendy

Open Access

Homogeneous Real-Time Detection of Single-Nucleotide Polymorphisms by Strand Displacement Amplification on the BD ProbeTec ET System

Author(s) -

Shasha Wang,

Keith Thornton,

Andrew M. Kuhn,

James G. Nadeau,

T. J. Hellyer

Publication year - 2003

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/49.10.1599

Subject(s) - buccal swab , loop mediated isothermal amplification , single nucleotide polymorphism , genotype , microbiology and biotechnology , biology , allele , multiplex , dna , genetics , gene

The BD ProbeTec ET System is based on isothermal strand displacement amplification (SDA) of target nucleic acid coupled with homogeneous real-time detection using fluorescent probes. We have developed a novel, rapid method using this platform that incorporates a universal detection format for identification of single-nucleotide polymorphisms (SNPs) and other genotypic variations.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research