Quantitative Analysis of Tyrosine Hydroxylase mRNA for Sensitive Detection of Neuroblastoma Cells in Blood and Bone Marrow
Author(s) -
Catarina Träger,
Per Kogner,
Magnus Lindskog,
Frida Ponthan,
Anita Kullman,
Bertil Kågedal
Publication year - 2003
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/49.1.104
Subject(s) - neuroblastoma , tyrosine hydroxylase , bone marrow , minimal residual disease , messenger rna , medicine , tyrosine , pathology , endocrinology , biology , immunohistochemistry , gene , biochemistry , cell culture , genetics
Sensitive monitoring of minimal residual disease may improve the treatment of neuroblastoma in children. To detect and monitor neuroblastoma cells in blood and bone marrow, we developed a quantitative method for the analysis of tyrosine hydroxylase mRNA.
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