Coping with Stress and the Emergence of Multidrug Resistance in Fungi | Zendy

Erika Shor | Zendy; David S. Perlin | Zendy

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Coping with Stress and the Emergence of Multidrug Resistance in Fungi

Author(s) -

Erika Shor,

David S. Perlin

Publication year - 2015

Publication title -

plos pathogens

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.719

H-Index - 206

eISSN - 1553-7374

pISSN - 1553-7366

DOI - 10.1371/journal.ppat.1004668

Subject(s) - drug resistance , multiple drug resistance , biology , fluconazole , antifungal drug , antifungal , drug , echinocandins , cryptococcus , immunology , medicine , microbiology and biotechnology , pharmacology , caspofungin

The incidence of invasive fungal infections poses a serious global health threat, killing nearly 1.4 million people a year—a number comparable to deaths from tuberculosis. Factors that contribute to this disease burden and high mortality include insufficient diagnostics and treatment, and the increasing numbers of individuals with immune system defects who are particularly susceptible to fungal pathogens [1].

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