Are We There Yet? The Smallpox Research Agenda Using Variola Virus | Zendy

Inger K. Damon | Zendy; Clarissa R. Damaso | Zendy; Grant McFadden | Zendy

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Are We There Yet? The Smallpox Research Agenda Using Variola Virus

Author(s) -

Inger K. Damon,

Clarissa R. Damaso,

Grant McFadden

Publication year - 2014

Publication title -

plos pathogens

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.719

H-Index - 206

eISSN - 1553-7374

pISSN - 1553-7366

DOI - 10.1371/journal.ppat.1004108

Subject(s) - smallpox , variola virus , safer , smallpox virus , public health , virology , work (physics) , political science , medical research , medicine , biology , vaccinia , vaccination , computer science , computer security , pathology , gene , recombinant dna , mechanical engineering , biochemistry , engineering

Despite significant advances, there is more work to be done before the international community can be confident that it possesses sufficient protection against any future smallpox threats. The current World Health Organization (WHO)-approved research agenda for smallpox has been tightly focused by the interpretation that research “essential for public health” equates solely to applied research related directly to the development of new antiviral drugs, safer vaccines, and better diagnostics. Despite considerable advances in this direction, we argue that the research agenda with live variola virus is not yet finished and that significant gaps still remain.

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