Spectroscopic (UV/VIS, Raman) and Electrophoresis Study of Cytosine-Guanine Oligonucleotide DNA Influenced by Magnetic Field | Zendy

Seyedeh Maryam Banihashemian | Zendy; Vengadesh Periasamy | Zendy; Boon Tong Goh | Zendy; Saadah Abdul Rahman | Zendy

Open Access

Spectroscopic (UV/VIS, Raman) and Electrophoresis Study of Cytosine-Guanine Oligonucleotide DNA Influenced by Magnetic Field

Author(s) -

Seyedeh Maryam Banihashemian,

Vengadesh Periasamy,

Boon Tong Goh,

Saadah Abdul Rahman

Publication year - 2016

Publication title -

plos one

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.99

H-Index - 332

ISSN - 1932-6203

DOI - 10.1371/journal.pone.0149488

Subject(s) - guanine , oligonucleotide , cytosine , raman spectroscopy , dna , magnetic field , nuclear magnetic resonance , materials science , chemistry , biophysics , biology , physics , optics , nucleotide , biochemistry , quantum mechanics , gene

Studying the effect of a magnetic field on oligonucleotide DNA can provide a novel DNA manipulation technique for potential application in bioengineering and medicine. In this work, the optical and electrochemical response of a 100 bases oligonucleotides DNA, cytosine-guanine (CG 100 ), is investigated via exposure to different magnetic fields (250, 500, 750, and 1000 mT). As a result of the optical response of CG 100 to the magnetic field, the ultra-violet-visible spectrum indicated a slight variation in the band gap of CG 100 of about 0.3 eV. Raman spectroscopy showed a significant deviation in hydrogen and phosphate bonds’ vibration after exposure to the magnetic field. Oligonucleotide DNA mobility was investigated in the external electric field using the gel electrophoresis technique, which revealed a small decrease in the migration of CG 100 after exposure to the magnetic field.

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