Correction: MiR-506 Is Down-Regulated in Clear Cell Renal Cell Carcinoma and Inhibits Cell Growth and Metastasis via Targeting FLOT1 | Zendy

FengQiang Yang | Zendy; Haimin Zhang | Zendy; Chen Shao-jun | Zendy; Yan Yang | Zendy; Jun-hua Zheng | Zendy

Open Access

Correction: MiR-506 Is Down-Regulated in Clear Cell Renal Cell Carcinoma and Inhibits Cell Growth and Metastasis via Targeting FLOT1

Author(s) -

FengQiang Yang,

Haimin Zhang,

Chen Shao-jun,

Yan Yang,

Jun-hua Zheng

Publication year - 2015

Publication title -

plos one

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.99

H-Index - 332

ISSN - 1932-6203

DOI - 10.1371/journal.pone.0129404

Subject(s) - metastasis , clear cell renal cell carcinoma , renal cell carcinoma , cell growth , cell , cancer research , carcinoma cell , biology , microbiology and biotechnology , medicine , cancer , tumor cells , biochemistry

miR-506 expression was detected in renal cancer cell lines 786-O, ACHN, Caki-1, and Caki-2 and ccRCC specimens by quantitative real-time-PCR. We assessed the association of miR-506 expression with pathology and prognosis in ccRCC patients. We over-expressed and knocked-down miR-506 expression in two renal cancer cell lines, 786-O and ACHN, and assessed the impact on cell proliferation, migration and invasion. A luciferase reporter assay was conducted to confirm the target gene of miR-506 in renal cancer cell lines.

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