Correction: Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength | Zendy

Emilie Louise Hansen | Zendy; Esin B. Sözer | Zendy; Stefania Romeo | Zendy; Stine K. Frandsen | Zendy; P. Thomas Vernier | Zendy; Julie Gehl | Zendy

Open Access

Correction: Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength

Author(s) -

Emilie Louise Hansen,

Esin B. Sözer,

Stefania Romeo,

Stine K. Frandsen,

P. Thomas Vernier,

Julie Gehl

Publication year - 2015

Publication title -

plos one

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.99

H-Index - 332

ISSN - 1932-6203

DOI - 10.1371/journal.pone.0128034

Subject(s) - calcium , electroporation , irreversible electroporation , programmed cell death , chemistry , biophysics , medicine , biology , apoptosis , biochemistry , gene

Electroporation, a method for increasing the permeability of membranes to ions and small molecules, is used in the clinic with chemotherapeutic drugs for cancer treatment (electrochemotherapy). Electroporation with calcium causes ATP (adenosine triphosphate) depletion and cancer cell death and could be a novel cancer treatment. This study aims at understanding the relationship between applied electric field, calcium concentration, ATP depletion and efficacy.

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