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Ultrasonic Elastography Features of Phyllodes Tumors of the Breast: A Clinical Research
Author(s) -
Lujing Li,
Hong Zeng,
Bing Ou,
Baoming Luo,
Xiaoyun Xiao,
Wenjing Zhong,
Xinbao Zhao,
Zizhuo Zhao,
Hai-Yun Yang,
Hui Zhi
Publication year - 2014
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0085257
Subject(s) - fibroadenoma , medicine , elastography , phyllodes tumor , ultrasound , radiology , pathological , ultrasonography , ultrasound elastography , breast ultrasound , pathology , mammography , breast cancer , cancer
The purpose of this study was to analyze the ultrasonic elastography features of phyllodes tumors of the breast comparing with fibroadenomas. A retrospective database was queried for the patients diagnosed as phyllodes tumors and fibroadenomas at Sun Yat-sen Memorial Hospital from January 2008 to August 2012. Three hundred and fifty lesions from 323 consecutive patients were included in the study. All the cases were examined by conventional ultrasonography and ultrasound elastography. Ultrasound elastography was used to calculate strain ratio of the lesions with bilateral breast tissue at the same depth as reference. There were 36 phyllodes tumors (27 benign, 8 borderline, 1 malignant) and 314 fibroadenomas (158 the pericanalicular type, 103 the intracanalicular type, 53 other special types). The strain ratio for phyllodes tumors (3.19±2.33) was significantly higher than for fibroadenomas (1.69±0.88) (p<0.05). The Spearman . s correlation coefficient between strain ratio of ultrasound elastography and pathological groups was significant, with a value of 0.17 (p<0.05). Ultrasound elastography could provide additional information to differentiate phyllodes tumors from fibroadenoma in breast.

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