SOX9 Duplication Linked to Intersex in Deer | Zendy

Regina Kropatsch | Zendy; Gabriele Dekomien | Zendy; Denis A. Akkad | Zendy; Wanda M. Gerding | Zendy; Elisabeth PetraschParwez | Zendy; Neil D. Young | Zendy; Janine Altmüller | Zendy; Peter Nürnberg | Zendy; Robin B. Gasser | Zendy; Jörg T. Epplen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

SOX9 Duplication Linked to Intersex in Deer

Author(s) -

Regina Kropatsch,

Gabriele Dekomien,

Denis A. Akkad,

Wanda M. Gerding,

Elisabeth PetraschParwez,

Neil D. Young,

Janine Altmüller,

Peter Nürnberg,

Robin B. Gasser,

Jörg T. Epplen

Publication year - 2013

Publication title -

plos one

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.99

H-Index - 332

ISSN - 1932-6203

DOI - 10.1371/journal.pone.0073734

Subject(s) - biology , testis determining factor , sox9 , genetics , gene duplication , gene , genotype , phenotype , disorders of sex development , genome , roe deer , evolutionary biology , y chromosome , zoology , gene expression

A complex network of genes determines sex in mammals. Here, we studied a European roe deer with an intersex phenotype that was consistent with a XY genotype with incomplete male-determination. Whole genome sequencing and quantitative real-time PCR analyses revealed a triple dose of the SOX9 gene, allowing insights into a new genetic defect in a wild animal.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research