Highly Efficient NMR Assignment of Intrinsically Disordered Proteins: Application to B- and T Cell Receptor Domains | Zendy

Linnéa Isaksson | Zendy; Maxim Mayzel | Zendy; Maria Saline | Zendy; Anders Pedersen | Zendy; Joakim Rosenlöw | Zendy; Bernhard Brutscher | Zendy; Göran Karlsson | Zendy; Vladislav Orekhov | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Highly Efficient NMR Assignment of Intrinsically Disordered Proteins: Application to B- and T Cell Receptor Domains

Author(s) -

Linnéa Isaksson,

Maxim Mayzel,

Maria Saline,

Anders Pedersen,

Joakim Rosenlöw,

Bernhard Brutscher,

Göran Karlsson,

Vladislav Orekhov

Publication year - 2013

Publication title -

plos one

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.99

H-Index - 332

ISSN - 1932-6203

DOI - 10.1371/journal.pone.0062947

Subject(s) - computational biology , characterization (materials science) , resampling , chemistry , computer science , biology , nanotechnology , algorithm , materials science

We present an integrated approach for efficient characterization of intrinsically disordered proteins. Batch cell-free expression, fast data acquisition, automated analysis, and statistical validation with data resampling have been combined for achieving cost-effective protein expression, and rapid automated backbone assignment. The new methodology is applied for characterization of five cytosolic domains from T- and B-cell receptors in solution.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research