Serotype Diversity of Astroviruses in Rawalpindi, Pakistan during 2009–2010 | Zendy

Muhammad Masroor Alam | Zendy; Adnan Khurshid | Zendy; Muhammad Suleman Rana | Zendy; Shahzad Shaukat | Zendy; Salmaan Sharif | Zendy; Mehar Angez | Zendy; Muhammad Naeem | Zendy; Syed Sohail Zahoor Zaidi | Zendy

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Serotype Diversity of Astroviruses in Rawalpindi, Pakistan during 2009–2010

Author(s) -

Muhammad Masroor Alam,

Adnan Khurshid,

Muhammad Suleman Rana,

Shahzad Shaukat,

Salmaan Sharif,

Mehar Angez,

Muhammad Naeem,

Syed Sohail Zahoor Zaidi

Publication year - 2013

Publication title -

plos one

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.99

H-Index - 332

ISSN - 1932-6203

DOI - 10.1371/journal.pone.0061667

Subject(s) - serotype , diarrhea , virology , biology , molecular epidemiology , genetic diversity , astrovirus , microbiology and biotechnology , rotavirus , genotype , medicine , genetics , virus , gene , environmental health , population

Astroviruses are globally known enteropathogens causing gastroenteritis and diarrhea, with eight well defined serotypes. Epidemiological studies have recognized serotype-1 as the most common subtype but no such data is available in Pakistan. During 2009–2010, we found astroviruses in 41 out of 535 (7%) samples collected from hospitalized children. Thirty one strains belonged to serotype-1 and clustered into two distinct lineages. Serotype-3, -4 and -6 were detected with 97–98% genetic homology to Indian and Chinese strains.

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