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Objective  Study the influence of household contact structure on the spread of an influenza-like illness. Examine whether changes to in-home care giving arrangements can significantly affect the household transmission counts.    Method  We simulate two different behaviors for the symptomatic person; either s/he remains at home in contact with everyone else in the household or s/he remains at home in contact with only the primary caregiver in the household. The two different cases are referred to as  full mixing  and  single caregiver , respectively.    Results  The results show that the  household’s cumulative transmission count  is lower in case of a  single caregiver  configuration than in the  full mixing  case. The household transmissions vary almost linearly with the household size in both  single caregiver  and  full mixing  cases. However the difference in household transmissions due to the difference in household structure grows with the household size especially in case of moderate flu.    Conclusions  These results suggest that details about human behavior and household structure do matter in epidemiological models. The policy of home isolation of the sick has significant effect on the household transmission count depending upon the household size.

Sensitivity of Household Transmission to Household Contact Structure and Size