Open AccessReduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study
Author(s) -
Anna RosanasUrgell,
Enmoore Lin,
Laurens Manning,
Patricia Rarau,
Moses Laman,
Nicolas Senn,
Brian T. Grimberg,
Livingstone Tavul,
Danielle I. Stanisic,
Leanne J. Robinson,
John J. Aponte,
Elijah Dabod,
John C. Reeder,
Peter Siba,
Peter A. Zimmerman,
Timothy M. E. Davis,
Christopher L. King,
P Michon,
Ivo Müeller
Publication year - 2012
Publication title -
plos medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.847
H-Index - 228
eISSN - 1549-1676
pISSN - 1549-1277
DOI - 10.1371/journal.pmed.1001305
Subject(s) - plasmodium vivax , odds ratio , malaria , cerebral malaria , medicine , plasmodium falciparum , cohort , genotyping , incidence (geometry) , tropical medicine , nested case control study , biology , gastroenterology , immunology , genotype , pathology , genetics , physics , gene , optics
Ivo Mueller and colleagues examined the association of Southeast Asian ovalocytosis with Plasmodium vivax infection by genotyping 1975 children enrolled in three independent epidemiological studies conducted in the Madang area of Papua New Guinea and assessing P. vivax infection and disease in the children.
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