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Ivo Mueller and colleagues examined the association of Southeast Asian ovalocytosis with  Plasmodium vivax  infection by genotyping 1975 children enrolled in three independent epidemiological studies conducted in the Madang area of Papua New Guinea and assessing  P. vivax  infection and disease in the children.

Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study