The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial | Zendy

Rajesh T. Gandhi | Zendy; Lu Zheng | Zendy; Ronald J. Bosch | Zendy; Ellen S. Chan | Zendy; David M. Margolis | Zendy; Sarah Read | Zendy; Beatrice Kallungal | Zendy; Sarah Palmer | Zendy; Kathy Medvik | Zendy; Michael M. Lederman | Zendy; Nadia Alatrakchi | Zendy; Jeffrey M. Jacobson | Zendy; Ann Wiegand | Zendy; Mary F. Kearney | Zendy; John M. Coffin | Zendy; John W. Mellors | Zendy; Joseph J. Eron | Zendy

Open Access

The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial

Author(s) -

Rajesh T. Gandhi,

Lu Zheng,

Ronald J. Bosch,

Ellen S. Chan,

David M. Margolis,

Sarah Read,

Beatrice Kallungal,

Sarah Palmer,

Kathy Medvik,

Michael M. Lederman,

Nadia Alatrakchi,

Jeffrey M. Jacobson,

Ann Wiegand,

Mary F. Kearney,

John M. Coffin,

John W. Mellors,

Joseph J. Eron

Publication year - 2010

Publication title -

plos medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.847

H-Index - 228

eISSN - 1549-1676

pISSN - 1549-1277

DOI - 10.1371/journal.pmed.1000321

Subject(s) - raltegravir , viremia , medicine , placebo , viral load , regimen , randomized controlled trial , gastroenterology , clinical endpoint , immunology , antiretroviral therapy , human immunodeficiency virus (hiv) , pathology , alternative medicine

Most HIV-1-infected patients on effective antiretroviral therapy (ART) with plasma HIV-1 RNA levels below the detection limits of commercial assays have residual viremia measurable by more sensitive methods. We assessed whether adding raltegravir lowered the level of residual viremia in such patients.

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