Polyclonal B Cell Differentiation and Loss of Gastrointestinal Tract Germinal Centers in the Earliest Stages of HIV-1 Infection | Zendy

Marc C. Levesque | Zendy; M. Anthony Moody | Zendy; Kwan-Ki Hwang | Zendy; Dawn J. Marshall | Zendy; John F. Whitesides | Zendy; Joshua D. Amos | Zendy; Thaddeus C. Gurley | Zendy; Sallie D. Allgood | Zendy; Benjamin B. Haynes | Zendy; Nathan Vandergrift | Zendy; Steven G. Plonk | Zendy; Daniel Parker | Zendy; Myron S. Cohen | Zendy; Georgia D. Tomaras | Zendy; Paul Goepfert | Zendy; George M. Shaw | Zendy; Jörn E. Schmitz | Zendy; Joseph J. Eron | Zendy; Nicholas J. Shaheen | Zendy; Charles B. Hicks | Zendy; Hua-Xin Liao | Zendy; Martin Markowitz | Zendy; Garnett Kelsoe | Zendy; David M. Margolis | Zendy; Barton F. Haynes | Zendy

Open Access

Polyclonal B Cell Differentiation and Loss of Gastrointestinal Tract Germinal Centers in the Earliest Stages of HIV-1 Infection

Author(s) -

Marc C. Levesque,

M. Anthony Moody,

Kwan-Ki Hwang,

Dawn J. Marshall,

John F. Whitesides,

Joshua D. Amos,

Thaddeus C. Gurley,

Sallie D. Allgood,

Benjamin B. Haynes,

Nathan Vandergrift,

Steven G. Plonk,

Daniel Parker,

Myron S. Cohen,

Georgia D. Tomaras,

Paul Goepfert,

George M. Shaw,

Jörn E. Schmitz,

Joseph J. Eron,

Nicholas J. Shaheen,

Charles B. Hicks,

Hua-Xin Liao,

Martin Markowitz,

Garnett Kelsoe,

David M. Margolis,

Barton F. Haynes

Publication year - 2009

Publication title -

plos medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.847

H-Index - 228

eISSN - 1549-1676

pISSN - 1549-1277

DOI - 10.1371/journal.pmed.1000107

Subject(s) - germinal center , polyclonal antibodies , immunology , biology , antibody , gut associated lymphoid tissue , b cell , virology , immune system

Studying the effects of early HIV infection on human antibody responses, M. Anthony Moody and colleagues find rapid polyclonal B cell differentiation and structural damage to gut-associated lymphoid tissue.

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