Integrating Bioinformatics Tools to Handle Glycosylation
Author(s) -
Yuliet Mazola,
Glay Chinea,
Alexis Musacchio
Publication year - 2011
Publication title -
plos computational biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.628
H-Index - 182
eISSN - 1553-7358
pISSN - 1553-734X
DOI - 10.1371/journal.pcbi.1002285
Subject(s) - glycosylation , computational biology , bioinformatics , computer science , biology , genetics
This tutorial is planned for biologists and computational biologists interested in bioinformatics applications to study protein glycosylation. Glycosylation is a co- and post-translational modification that involves the selective attachment of carbohydrates to proteins. The enhancement of glycosylation by applying glycoengineering strategies has become widely used to improve properties for protein therapeutics. In this tutorial, the use of bioinformatics to assist the rational design and insertion of N-glycosylation sites in proteins is described.
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