Open AccessCellular Defense Enzyme Drives Exceptionally High Rate of Mutation in HIV
Author(s) -
Richard Robinson
Publication year - 2015
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1002252
Subject(s) - biology , mutation , mutation rate , cytidine deaminase , genetics , human immunodeficiency virus (hiv) , enzyme , cytidine , microbiology and biotechnology , virology , biochemistry , gene
HIV-1 is already known to have an extremely fast mutation rate, but a new study shows it to be more than two orders of magnitude higher than previously believed, and that this is largely due to host cytidine deaminases. Read the Research Article.
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