Open AccessDistinct Brain Systems Mediate the Effects of Nociceptive Input and Self-Regulation on Pain
Author(s) -
ChoongWan Woo,
Mathieu Roy,
Jason T. Buhle,
Tor D. Wager
Publication year - 2015
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1002036
Subject(s) - functional magnetic resonance imaging , neuroscience , nociception , ventromedial prefrontal cortex , nucleus accumbens , cognition , neuroimaging , noxious stimulus , prefrontal cortex , chronic pain , stimulus (psychology) , psychology , cognitive psychology , central nervous system , medicine , receptor
Two distinct parallel neural systems independently contribute to our overall experience of pain – separately modulated by noxious input and by cognitive self-regulation.
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