Open AccessEvolution of RNA-Protein Interactions: Non-Specific Binding Led to RNA Splicing Activity of Fungal Mitochondrial Tyrosyl-tRNA Synthetases
Author(s) -
Lilian T. Lamech,
Anna L. Mallam,
Alan M. Lambowitz
Publication year - 2014
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1002028
Subject(s) - biology , rna , transfer rna , rna splicing , rna binding protein , rna editing , genetics , biochemistry , gene
Studies of tRNA synthetases that adapted to assist the splicing of group I introns provide insight into how proteins can evolve new RNA-binding functions.
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