Open AccessStructural and Mechanistic Basis of Zinc Regulation Across the E. coli Zur Regulon
Author(s) -
Benjamin A. Gilston,
Suning Wang,
Mason D. Marcus,
Mónica A. Canalizo-Hernández,
Elden P. Swindell,
Yi Xue,
Alfonso Mondragón,
Thomas V. O’Halloran
Publication year - 2014
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001987
Subject(s) - regulon , biology , zinc , computational biology , genetics , escherichia coli , gene , materials science , metallurgy
Structural, thermodynamic, and gene expression studies provide a comprehensive picture of how the bacterial metalloregulatory transcriptional repressor Zur achieves its exquisite sensitivity to zinc concentrations.
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