A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria
Author(s) -
Sujoy Lahiri,
Jesse T. Chao,
Shabnam Tavassoli,
Andrew K. Wong,
Vineet Choudhary,
Barry P. Young,
Christopher Loewen,
William A. Prinz
Publication year - 2014
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001969
Subject(s) - microbiology and biotechnology , endoplasmic reticulum , mitochondrion , biology , phosphatidylethanolamine , membrane contact site , translocase of the outer membrane , mitochondrial membrane transport protein , inner mitochondrial membrane , integral membrane protein , membrane protein , phospholipid , biochemistry , membrane , phosphatidylcholine
Tethering of the endoplasmic reticulum to mitochondria by a conserved endoplasmic reticulum complex is needed for the transfer of phospholipids between these organelles.
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