Variable Combinations of Specific Ephrin Ligand/Eph Receptor Pairs Control Embryonic Tissue Separation | Zendy

Nazanin Rohani | Zendy; Andrea Parmeggiani | Zendy; Rudolf Winklbauer | Zendy; François Fagotto | Zendy

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Variable Combinations of Specific Ephrin Ligand/Eph Receptor Pairs Control Embryonic Tissue Separation

Author(s) -

Nazanin Rohani,

Andrea Parmeggiani,

Rudolf Winklbauer,

François Fagotto

Publication year - 2014

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001955

Subject(s) - ephrin , erythropoietin producing hepatocellular (eph) receptor , biology , ectoderm , mesoderm , notochord , microbiology and biotechnology , xenopus , embryonic stem cell , anatomy , genetics , embryo , embryogenesis , receptor tyrosine kinase , signal transduction , gene

Vertebrate embryonic cells recognize self from non-self, thus restricting repulsion at tissue boundaries, through a combination of multiple ephrins and Eph receptors, simply based on binding selectivity and asymmetric expression.

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