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Adaptive Evolution and Environmental Durability Jointly Structure Phylodynamic Patterns in Avian Influenza Viruses
Author(s) -
Benjamín Roche,
John M. Drake,
Justin D. Brown,
David E. Stallknecht,
Trevor Bedford,
Pejman Rohani
Publication year - 2014
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001931
Subject(s) - biology , phylogenetic tree , viral evolution , evolutionary biology , genetic diversity , phylogenetics , evolutionary ecology , influenza a virus subtype h5n1 , phylogenetic diversity , transmission (telecommunications) , ecology , pandemic , influenza a virus , host (biology) , coevolution , zoology , genetics , virus , genome , covid-19 , gene , population , infectious disease (medical specialty) , pathology , sociology , engineering , medicine , demography , disease , electrical engineering
Avian influenza viruses show high genetic diversity, but give rise to pandemic human influenza strains which are much less diverse; we show that these contrasting degrees of viral diversity can be explained by both host (demography) and viral (environmental durability and mutability) factors.

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