Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study
Author(s) -
Mariam JamalHanjani,
A. Hackshaw,
Yenting Ngai,
Jacqui Shaw,
Caroline Dive,
Sergio A. Quezada,
Gary Middleton,
Elza de Bruin,
John Le Quesne,
Seema Shafi,
Mary Falzon,
Stuart Horswell,
Fiona Blackhall,
Iftekhar Khan,
Sam M. Janes,
M. Nicolson,
David Lawrence,
Martin Förster,
Dean A. Fennell,
SM Lee,
J.F. Lester,
Keith M. Kerr,
S. Muller,
Natasha Iles,
Sean D. Smith,
Nirupa Murugaesu,
Richard Mitter,
Max Salm,
Aengus Stuart,
Nik Matthews,
Haydn Adams,
Tanya Ahmad,
Richard Attanoos,
Jonathan Bennett,
Nicolai J. Birkbak,
Richard Booton,
Ged Brady,
Keith Buchan,
Arrigo Capitano,
Mahendran Chetty,
Mark Cobbold,
Philip Crosbie,
Helen Davies,
Alan Denison,
Madhav Djearman,
Jacki Goldman,
Tom Haswell,
Leena Dennis Joseph,
Malgorzata Kornaszewska,
Matthew Krebs,
Gerald Langman,
Mairead MacKenzie,
Joy Millar,
Bruno Morgan,
Babu Naidu,
Daisuke aka,
Karl S. Peggs,
Catrin Pritchard,
Hardy Remmen,
Andrew Rowan,
Rajesh Shah,
Elaine Smith,
Yvonne Summers,
Magali N. Taylor,
Selvaraju Veeriah,
David Waller,
Ben Wilcox,
Maggie Wilcox,
Ian Woolhouse,
Nicholas McGranahan,
Charles Swanton
Publication year - 2014
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001906
Subject(s) - biology , lung cancer , precision medicine , cancer , somatic evolution in cancer , tracking (education) , computational biology , bioinformatics , genetics , oncology , medicine , psychology , pedagogy
TRACERx, a prospective study of patients with primary non-small cell lung cancer, aims to map the genomic landscape of lung cancer by tracking clonal heterogeneity and tumour evolution from diagnosis to relapse.
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